Recent Sensitivity Pattern of Salmonella Typhi in a tertiary care Hospital

Salmonella typhi is the main cause of enteric fever in Homo sapiens. The topic concern now a day emerging multidrug resistance. It causes disease intestinal tract known as fever, while paratyphi paratyphoid fever. This infection waterborne and foodborne. Approximately 12 – 33 million people suffered from typhoid annually around globe. Objective: aim study was to evaluate sensitivity patterns paratyphi. retrospective study, conducted at Medicine Department Sahara Medical College, Narowal Rawalpindi University, Rawalpindi. Methods: blood sample 306 patients visiting teaching hospital our institute were collected. samples tested antimicrobial sensitivity. Kirby-Bauer disc diffusion method used. E-test leveraged for obtaining MIC ciprofloxacin, agar dilution utilized azithromycin. Results: collected patients. Out sample, 177 S. other 127 typhi. 56% showed ciprofloxacin antibiotic, 281 nalidixic antibody. According criteria 94% isolate susceptible 46% While 31% resistant it. 90% ampicillin 95% trimoxazole. Conclusion: co-trimoxazole care highly suggested management Ciprofloxacin resistance cannot be accurately measured by Nalidixic acid screening. also showcased against